Cheon K, Ozene N. Effect of gold nanoparticle on blood lipid
profile test. Adv Lab Med Int. 2018; 8: 43 - 46.
ABSTRACT
Dyslipidemia is a common
metabolic disorder that can be seen worldwide. To diagnose and monitor the
problem, blood lipid profile test is necessary. Here, the authors report an
observation on effect of nanoparticle on the blood lipid profile test result. A
laboratory experiment was done in a medical laboratory. Totally 100 blood
samples were used in this experiment. All samples are analyzed by the same
clinical chemistry analyzer at the same laboratory condition. Each sample was
separated into 2 parts; the first is added with a droplet of gold nanoparticle
solution and the second part is not. It can be seen that there is a significant
difference of lipid profile test results. In the present day, there are many
new nanosubstance that human can expose daily. The interference effect of the
nanoparticle on the lipid profile test should be recognized in the present era
of emerging nanotechnology. The great concern should be raised when the new
nanodrug is used. In fact, the new nanodrug relating to dysplipidemia such as fenofibrate
nanoparticle tablet formulation is already used in clinical practice.
Keywords: effect, gold nanoparticle, lipid profile
