Effects of low pressure hypoxia on oxidation - antioxidant system of athletes

EFFECTS OF LOW PRESSURE HYPOXIA ON OXIDATION – ANTIOXIDANT SYSTEM OF ATHLETES

            

Li ZZ. Effects of low pressure hypoxia on oxidation - antioxidant system of athletes. Case Study Case Rep. 2018; 8(1): 1 - 8.

ABSTRACT

The aim of this work is to study the effect of hypobaric hypoxia on the oxidative-antioxidant system of volleyball players, and to provide a safe and reliable clinical treatment for cardiovascular disease. Eight volleyball athletes trained on low altitude and low oxygen in a plateau on May 12, 2017 were listed as observation group, and 20 athletes trained in normothermic normoxia were selected. (P <0.05). The levels of superoxide dismutase (SOD) and catalase (CAT) in the brain tissue of the two groups were significantly higher than those in the control group (P <0.05), and the levels of mitochondrial malondialdehyde (MDA) And myocardial mitochondrial free Ca^{2 +} levels. The levels of SOD and CAT in the observation group were lower than those in the control group (P <0.05), and the level of SOD and CAT in the observation group was the highest (P <0.05). The expression of Cygb in the observation group was higher than that in the control group. The level of Cygb in the observation group was higher than that in the control group (P <0.05, t = 2.8676). The myocardial mitochondrial free Ca2 + level in the observation group was lower than that in the control group, P < 0.05, t = 5.8190. Volleyball player's oxidation-oxidation system is related to the generation of oxygen free radicals. It can be judged by monitoring the parameters such as SOD, CAT, Cygb, MDA, ATP, Ca^{2 +} and other indicators in the brain tissue during the daily life signs of athletes. According to the principle of relevance, take CIHH for treatment.

Keywords: Volleyball player, oxidation - antioxidant system, low pressure hypoxia, SOD, CAT

Pierre Robin Sequence: A clinical case presentation

PIERRE ROBIN SEQUENCE: A CLINICAL CASE PRESENTATION

  

Al hojaili N, Kutbi I, Al Zahrani AS, Al malky H. Pierre Robin Sequence: A clinical case presentation. Case Study Case Rep. 2018; 8(1): 9 - 12.

                                                                                                                        

ABSTRACT

Pierre Robin sequence (PRS) indicates the association of glossoptosis, micrognathia and airway blocking. Cases immediately after birth with severe dyspnea due to upper airway blocking are very unusual with this syndrome. We reported a case with PRS who developed severe dyspnea due to morphological abnormality immediately after birth and were rescued for short time by fiberoptic nasotracheal intubation. The patient had micrognathia and cleft palate, and his tongue protruded into the nasal cavity via a cleft palate. He was diagnosed as Pierre Robin sequence due to his invaginated tongue was considered an extreme type of glossoptosis. The patient also accompanied some anomalad. Unaccepted, her chromosome analysis showed a normal configuration. Moreover, tongue protruded into the nasal cavity via a cleft palate occupied pharynx and nasal cavity, resulting in severe dyspnea. Therefore, fiberoptic nasotracheal intubation was done to secure the airway for resuscitation. PRS case with extreme type of glossoptosise require resuscitation by fiberoptic intubation immediately after birth. As such, neonatologists should obtain the skill of fiberoptic intubation.

Keywords: Case presentation, Pierre Robin sequence, Glossoptosis, Micrognathia, Airway blocking, Fiberoptic nasotracheal intubation