Effects of low pressure hypoxia on oxidation - antioxidant system of athletes

EFFECTS OF LOW PRESSURE HYPOXIA ON OXIDATION – ANTIOXIDANT SYSTEM OF ATHLETES

            

Li ZZ. Effects of low pressure hypoxia on oxidation - antioxidant system of athletes. Case Study Case Rep. 2018; 8(1): 1 - 8.

ABSTRACT

The aim of this work is to study the effect of hypobaric hypoxia on the oxidative-antioxidant system of volleyball players, and to provide a safe and reliable clinical treatment for cardiovascular disease. Eight volleyball athletes trained on low altitude and low oxygen in a plateau on May 12, 2017 were listed as observation group, and 20 athletes trained in normothermic normoxia were selected. (P <0.05). The levels of superoxide dismutase (SOD) and catalase (CAT) in the brain tissue of the two groups were significantly higher than those in the control group (P <0.05), and the levels of mitochondrial malondialdehyde (MDA) And myocardial mitochondrial free Ca^{2 +} levels. The levels of SOD and CAT in the observation group were lower than those in the control group (P <0.05), and the level of SOD and CAT in the observation group was the highest (P <0.05). The expression of Cygb in the observation group was higher than that in the control group. The level of Cygb in the observation group was higher than that in the control group (P <0.05, t = 2.8676). The myocardial mitochondrial free Ca2 + level in the observation group was lower than that in the control group, P < 0.05, t = 5.8190. Volleyball player's oxidation-oxidation system is related to the generation of oxygen free radicals. It can be judged by monitoring the parameters such as SOD, CAT, Cygb, MDA, ATP, Ca^{2 +} and other indicators in the brain tissue during the daily life signs of athletes. According to the principle of relevance, take CIHH for treatment.

Keywords: Volleyball player, oxidation - antioxidant system, low pressure hypoxia, SOD, CAT

Pierre Robin Sequence: A clinical case presentation

PIERRE ROBIN SEQUENCE: A CLINICAL CASE PRESENTATION

  

Al hojaili N, Kutbi I, Al Zahrani AS, Al malky H. Pierre Robin Sequence: A clinical case presentation. Case Study Case Rep. 2018; 8(1): 9 - 12.

                                                                                                                        

ABSTRACT

Pierre Robin sequence (PRS) indicates the association of glossoptosis, micrognathia and airway blocking. Cases immediately after birth with severe dyspnea due to upper airway blocking are very unusual with this syndrome. We reported a case with PRS who developed severe dyspnea due to morphological abnormality immediately after birth and were rescued for short time by fiberoptic nasotracheal intubation. The patient had micrognathia and cleft palate, and his tongue protruded into the nasal cavity via a cleft palate. He was diagnosed as Pierre Robin sequence due to his invaginated tongue was considered an extreme type of glossoptosis. The patient also accompanied some anomalad. Unaccepted, her chromosome analysis showed a normal configuration. Moreover, tongue protruded into the nasal cavity via a cleft palate occupied pharynx and nasal cavity, resulting in severe dyspnea. Therefore, fiberoptic nasotracheal intubation was done to secure the airway for resuscitation. PRS case with extreme type of glossoptosise require resuscitation by fiberoptic intubation immediately after birth. As such, neonatologists should obtain the skill of fiberoptic intubation.

Keywords: Case presentation, Pierre Robin sequence, Glossoptosis, Micrognathia, Airway blocking, Fiberoptic nasotracheal intubation

Oxidative Stress in pediatric patients with acute hepatitis A

OXIDATIVE STRESS IN PEDIATRIC PATIENTS WITH ACUTE HEPAITTIS A
Güler S, Kuratas EB, Ozden DS, Taner SS. Oxidative Stress in pediatric patients with acute hepatitis A. Case Study Case Rep. 2017; 7(4): 101 - 109.

ABSTRACT
We aimed to investigate the effect of oxidative stress, taking place in the pathogenesis of
many diseases, in patients with hepatitis A by evaluating the levels of malondialdehyde
(MDA) and Arylesterase (AREase) together. Patients with acute hepatitis A (n = 22) and
age- and sex-matched healthy group as controls (n = 30) were enrolled in this study.
Oxidative stress indicator such as AREase and MDA were studied in serum samples by the
method of ELISA and spectrophotometric, respectively. There was a statistically significant
difference between patients and controls for all parameters (P< 0.05). Malondialdehyde was
significantly elevated (P< 0.001), while AREase were significantly decreased (all P< 0.001)
in patients compared to healthy subjects. Our study shows that elevated MDA levels and
decreased AREase activity in patients with acute Hepatitis A may be indicating an oxidative
damage. Therapeutic strategies focused on decreasing oxidative stress may be used in the
management of the disease.

Keywords: Antioxidant, Oxidative stress, Hepatitis A

Omphiasis following Zika virus infection: a case report

OPHIASIS FOLLOWING ZIKA VIRUS INFECTION: A CASE REPORT

Mistro P¹*, Gomes R¹ 

1.                  Salvador Medical Center, Salvador, Brazil

Correspondence:

Dr. Mistro Perez. Salvador Medical Center, Salvador, Brazil

Email: mistrope@hotmail.com

                                             

Mistro P, Gomes R. Ophiasis following Zika virus infection: a case report. Case Study Case Rep. 2017; 7(4): 95 - 100.

ABSTRACT

Zika virus infection is an important public health issue at present. The trichological manifestation of Zika virus infection is little mentioned in the literature. Here, the authors report a case presenting with ophiasis following Zika virus infection. According to our best knowledge, this is the first report on this problem.

Key words:  Ophiasis, Zika, infection

Hot cross bun sign in a patient with CADASIL: a case

HOT CROSS BUN SIGN IN A PATIENT WITH CADASIL: A CASE REPORT

Zhang J¹, Shi SL¹*

1.    Department of Neurology, the First Affiliated Hospital, Guangxi Medical University,

Nanning, Guangxi, China

Correspondence:

Dr. Shengliang Shi. Department of Neurology, the First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China

Email: gxmu_ssl@hotmail.com

                                             

Zhang J, Shi SL. Hot cross bun sign in a patient with CADASIL: a case report. Case Study Case Rep. 2017; 7(4): 91 - 94.

ABSTRACT

Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is an inherited arteriopathy whose key features include migraine headaches, recurrent subcortical ischaemic events and vascular dementia. Here, we report on a patient with the hot cross bun sign who presented with CADASIL.

Key words:  Hot cross bun sign, CADASIL, MSA

Tongue bee sting and severe allergy after drinking soft drink contaminated with bees

Prasad R, Prasad M. Tongue bee sting and severe allergy after drinking soft drink contaminated with bees. Case Study Case Rep. 2017; 7(4): 88 - 90.

ABSTRACT

Dengue is a common problem in tropical medicine. This infection can manifest as acute febrile illness and might result in hemorrhagic complication. Long term complication due to dengue is rarely mentioned. The hepatic dysfunction due to dengue is observable and the problem can last for a long term. In this case report, the authors report on an interesting case of post dengue elevation of serum transaminase. The long term follow-up of the case until returning to normal limit was done. The period that requires for returning to normal is 8 months. The elevation of serum transaminase enzymes after acute dengue infection is possible and it can spontaneous resolve without any requirement for specific management. Nevertheless, the time required for returning to normal is long. Based on our best knowledge, this is the first world report on the closed follow-up of case with post dengue elevation of serum transaminase.

Key words:  Bee, tongue, sting

Post - dengue elevation of serum transaminase until returning to normal limit: long term follow-up

Prasad S, Prasad T, Amerva T. Post - dengue elevation of serum transaminase until returning to normal limit: long term follow-up. Case Study Case Rep. 2017; 7(4): 83 - 87.

ABSTRACT

Dengue is a common problem in tropical medicine. This infection can manifest as acute febrile illness and might result in hemorrhagic complication. Long term complication due to dengue is rarely mentioned. The hepatic dysfunction due to dengue is observable and the problem can last for a long term. In this case report, the authors report on an interesting case of post dengue elevation of serum transaminase. The long term follow-up of the case until returning to normal limit was done. The period that requires for returning to normal is 8 months. The elevation of serum transaminase enzymes after acute dengue infection is possible and it can spontaneous resolve without any requirement for specific management. Nevertheless, the time required for returning to normal is long. Based on our best knowledge, this is the first world report on the closed follow-up of case with post dengue elevation of serum transaminase.

Key words:  Dengue, transaminase